気管支肺胞洗浄(BAL)正常値 と 各種疾患での特徴 
normal findings of bronchoalveolar lavage & characteristics of particular disease

気管支肺胞洗浄の細胞分画 CD4/8比の正常値と
各種疾患での特徴を記載しています

  non-smoker smoker
total cell count(105/ml)
0.2-1.0 1.0-9.0
cell differentiation
   
    macrophage
75-95 92-99
    lymphocyte
4-25 2-5
    neutrophile
<3.0 <3.0
    eosinophile
<1.0 <1.0
T cell subset
   
    CD4+
33-57 19-37
    CD8+
14-28 27-54
    CD4/CD8

1.5-3.2 0.4-1.0

increase of lymphocyte:
    *hypersensitivity pneumonitis
    *sarcoidosis
    *viral pneumonia
    *mycoplasma pneumonia
    *non-specific pneumonitis

increase of neutrophil:
    *bacterial pneumonia
    *diffuse panbronchiolitis
    *bronchiectasis
    *adult respiratory distress syndrome(ARDS)
    *idiopathic pulmonary fibrosis
    *cryptogenic organizing pneumonia

increase of eosinophil
    *eosinophilic pneumonia
    *drug induced pneumonitis(depends on the situation)
    *desquamative interstitial pneumonia

increase of CD4/8 proportion
    *sarcoidosis
    *hypersensitivity pneumonitis (farmer's lung)
    *pulmonary Langerhans cell histiocytosis

decrease of CD4/8 proportion
    *summer-type hypersensitivity pneumonia
    *acquired immune deficiency syndrome (AIDS)
    *miliary tuberculosis

気管支肺胞洗浄(BAL)正常値 と 各種疾患での特徴 
normal findings of bronchoalveolar lavage & characteristics of particular disease
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